Supplement may help burn fat long after exercise. The gut bacteria produce an appetite suppressant that can enhance the effect of an exercise-based weight loss program.
The number of health benefits regular exercise is well known. However, its impact on weight loss is less clear, since exercise increases appetite, potentially leading to an increase in calorie intake.
A new study published in the journal Metabolism presents a possible solution.
The research comes from the Scottish Universities Environmental Research Center, the universities of Glasgow and the West of Scotland, and Imperial College London, all of which are located in the United Kingdom.
He suggests that adding some appetite suppressant supplement to moderate exercise increases the likelihood of weight loss, even without a change in diet.
The Biotechnology and Biological Sciences Research Council-funded this research.
The study explored a supplement called inulin-propionate ester (IPE).
Propionate is a short-chain fatty acid produced by the digestion of dietary fiber by gut microbes. It is a natural and effective appetite suppressant.
Propionate breaks down quickly in the body, to enhance its effect, scientists have chemically linked it to inulin. It is a fiber common to garlic, Jerusalem artichoke, chicory and onion. The result is IPE.
As the author of the corresponding study notes, Douglas Morrison, “there is currently a lot of interest in how our gut microbiota affects our health and well-being.”
Research has also found that PEI suppresses the urge to eat high-calorie foods. For example, those to whom researchers offered all the pasta they could eat ended up eating 10% less than usual.
Their new study found that PEI can improve the weight loss effects of a moderate exercise program without requiring dietary changes.
As Morrison explains, “What we were able to show for the first time is that this latter effect continues when exercise is added to the regular intake of PEI. The study did not examine the effectiveness of dieting, exercise and PEI.
The trial included 20 women between the ages of 25 and 45. Each had a body mass index (BMI) greater than 25. The trial lasted 4 weeks.
The team divided the participants into two groups of 10. Both groups participated in moderate exercise programs.
One group received a supplement of PEI and the other received a placebo supplement containing cellulose. All participants maintained their normal eating habits throughout the trial.
The researchers measured resting fat oxidation levels before and after the test using blood and gas samples. They collected them before breakfast, after breakfast and after lunch.
Participants who exercised while taking the placebo showed no change in their rate of fat oxidation after the trials.
The group taking PEI, however, showed a significant increase in fat burning at rest, even 7 hours after their last dose of PEI.
The new study was small and short-lived, so its findings require further verification.
Study co-author Dalia Malkova said, “While these early results are promising, we should stress that there are limits to this study, which was conducted with a small group on just  weeks. ”
“For example, we cannot yet draw conclusions about how the increased fat oxidation. Combined with exercise could affect participants’ body composition and body mass.”
Researchers are seeking funding for new trials of PEI, involving more people and for a longer period of time.